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Broad-Spectrum Industrial Biocide and Preservative CAS 26172-55-4 for Water Treatment and More

  • Broad-Spectrum Industrial Biocide and Preservative CAS 26172-55-4 for Water Treatment and More
Place of Origin China
Brand Name HOYOSHEE
Certification ISO9001
Model Number HYS-55-4
Minimum Order Quantity Negotiation
Price Negotiation
Delivery Time 5-8 days
Payment Terms L/C,D/A,D/P,T/T,Western Union
Supply Ability 500 Ton/Month
Product Details
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Broad-Spectrum Industrial Biocide

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CAS 26172-55-4 Preservative

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Water Treatment Isothiazolinone
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Product Description
Kason/Kasson (CMIT) CAS 26172-55-4 Industrial Biocides and Preservatives
Product Information
CAS Number 26172-55-4
EINECS 247-500-7
Chemical Name 5-Chloro-2-methyl-4-isothiazolin-3-one

Isothiazolone derivatives are compounds containing an isothiazolone ring, representing a new class of broad-spectrum, highly effective non-oxidizing fungicides. Known for their high efficiency, environmental compatibility, and broad-spectrum properties, these biocides are widely used in industrial circulating cooling water, adhesives, textiles, coatings, emulsions, plastics, paper manufacturing, and various other fields.

Major Applications
Industrial Water Treatment
  • Cooling water systems
  • Oilfield injection water
  • Paper mill white water
  • Reverse osmosis membranes

Typical dosage: 80-300 mg/L

Paints and Coatings
  • Latex paints
  • Waterborne industrial coatings
  • Wood stains
  • Plasters and mortars

Typical dosage: 0.05-0.4% of active ingredient

Metalworking Fluids
  • Cutting fluids
  • Grinding fluids
  • Hydraulic fluids

Typical dosage: 0.1-0.2% (MIT/CMIT blends)

Adhesives and Sealants
  • Water-based adhesives
  • Caulks and sealants
  • Joint compounds
Personal Care and Cosmetics
  • Shampoos, conditioners (rinse-off products)
  • Liquid soaps
  • Wet wipes
  • Makeup removers
Regulatory Restrictions:
EU: MIT banned in leave-on products; MIT in rinse-off products ≤ 0.0015%; CMIT/MIT mixtures prohibited in leave-on products
China: Similar restrictions under GB/T 29666-2013
Household Products
  • Liquid detergents
  • Fabric softeners
  • All-purpose cleaners
  • Dishwashing liquids
Leather and Textiles
  • Leather tanning preservation
  • Textile finishing
  • Anti-mildew treatments
Marine Antifouling (DCOIT)
  • Ship hull paints
  • Marine structures
  • Fishing nets
Agriculture
  • Seed treatment
  • Rice blast control (patented uses)
Safety and Toxicology
⚠️ Important Safety Information
Health Hazards
Hazard Type Description
Skin Sensitization Strong contact allergen; most significant concern; sensitization can develop after repeated exposure
Skin Irritation Irritating to skin; prolonged contact may cause chemical burns
Eye Damage Causes serious eye damage (Category 1)
Respiratory Sensitization Inhalation may cause asthma-like reactions (occupational hazard reported)
Acute Toxicity Oral LD50 (rat): ~1000-1400 mg/kg (moderately toxic); dermal LD50 (rabbit): >2000 mg/kg
Toxicity Data (Kathon CMIT/MIT 3:1 blend)
Endpoint Value
Oral LD50 (rat) 1,000-1,400 mg/kg
Dermal LD50 (rabbit) >2,000 mg/kg
Inhalation LC50 (rat) 2.6-3.4 mg/L (4h)
Eye Irritation Corrosive (causes irreversible damage)
Skin Irritation Severe irritant
Skin Sensitization Strong sensitizer (potency: moderate to strong)
Ecotoxicity

Isothiazolinones are highly toxic to aquatic organisms:

Endpoint Value
Fish (LC50) 0.1-1.0 mg/L (96h)
Daphnia magna (EC50) 0.05-0.5 mg/L (48h)
Algae (EC50) 0.01-0.1 mg/L (72h)
Regulatory Classifications
Region Classification
GHS Acute Tox. 4 (Oral), Skin Corr. 1B/1C, Eye Dam. 1, Skin Sens. 1, Aquatic Acute 1
EU CLP H302 (Harmful if swallowed), H314 (Causes severe skin burns and eye damage), H317 (May cause an allergic skin reaction), H400 (Very toxic to aquatic life)
US EPA Registered pesticide; subject to FIFRA regulations
EU BPR Approved biocidal active substance; usage restricted under Biocidal Products Regulation (EU) 528/2012
Cosmetics Regulation EU: MIT ≤ 0.0015% (rinse-off only); CMIT/MIT mixtures prohibited in leave-on products; BIT and OIT banned in cosmetics
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Broad-Spectrum Industrial Biocide